I was wasting my time in michigan on runs I'll have to re-do with my main save. The problem I had was that I couldn't access the vehicle functions menu with gamepad up-hat, I had to use mouse action to get to the menu, but it was normal after that.
Had a similar issue today twice. With a wheel. Entered a "trailer store" and could not use neither the D-Pads up/down not keyboard with up&down. Exit game, reenter, everything OK. For me it looked like a "failure" in the input of the dialog box.