I have a recurrent issue (similar to the older thread) where my mouse button bindings are not recognised. I can go into the settings and set them up again, sometimes with a warning about duplicate binding (even though it's the same button as used before), the menu doesn't show MB3, MB4, or MB5, but some other binding ('4', '5', or whatever).
After a couple of rounds, the mouse buttons 'may' work again, but it's not a guarantee. It's quite annoying. Could be a Logitech thing, but the buttons DO work so they are recognised by the game, but not by the config settings.
Mouse : Logitech G pro Wireless.